Novel and promising approaches in COVID-19 treatment. (COVID-19 dedicated issue.)

Novel coronavirus or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe respiratory infectious disease, known as coronavirus disease-19 (COVID-19). Over the past few months, a considerable rise in the incidence rate and prevalence of COVID-19 infection have been witnessed. Considering the high disease burden and rapid spread of the COVID-19 and no effective treatment is currently existing, stem cells, engineered nanobiomaterials, natural killer cells based therapy, RNA metabolites and extracellular vesicles are promising alternatives to tackle devastating epidemic. This review spotlights the applications and potential of above-mentioned methods in the treatment of COVID-19.